epiLife のアプリ分析 5月24日

People age at different rates. Some “look” and “feel” older than their chronological age while others look younger than their chronological age. Our biological age is a better parameter of our health, well-being and life span than our chronological age. DNA is the hardware, genetics is the operating system, and DNA methylation and other epigenetic factors are the software that programs the genome. A paradigm shift in the search for biological age markers occurred with the discovery of the “epigenetic clock” by Horvath, which is based on the measurement of DNA methylation status at 500 strategic positions in DNA. Studies suggest that accelerated “epigenetic clock” might be associated with increased risk for several age-related chronic diseases such as cardiovascular disease and cancer at a later age (https://www.ncbi.nlm.nih.gov/pubmed/?term=epigenetic+clock+disease). However, this is still an open field and more studies are needed. Importantly, “epigenetics” is different from “genetics” and is potentially reversible by dietary interventions and lifestyle changes. Preliminary studies show that dietary changes can cause deceleration of the epigenetic clock in certain people (https://www.ncbi.nlm.nih.gov/pubmed/30350398), but this is still an open field. Our application is an opportunity to get the results of epigenetic age. At this stage, it has only informative content that allows you to study the result of your test and it is easy to handle. In the future, we are going to expand the functionality of this application by adding questionnaires. Disclaimer: This app is intended for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen on this app. If you think you may have a medical emergency, call your doctor or emergency services immediately.