ASH Pocket Guides vs CARTOX Usage & Stats

The ASH Pocket Guides app brings together all of ASH's pocket guides to provide guidance for the diagnosis and management of a variety of hematologic conditions. Key features include: New search and favorites features allow you to quickly access tools and guides you use regularly. Click the heart icon to elevate pocket guides or tools to the top of the list. All of ASH's currently available pocket guides, including: • Acute Leukemia – Initial Diagnostic Workup • Anticoagulant Dosing • Monoclonal Gammopathy of Undetermined Significance (MGUS) • Red Blood Cell Transfusion • Management of Acute Complications of Sickle Cell Disease • Health Maintenance and Management of Chronic Complications of Sickle Cell Disease • Hydroxyurea and Transfusion Therapy for the Treatment of Sickle Cell Disease • Heparin Induced Thrombocytopenia (HIT) • Immune Thrombocytopenia (ITP) • Thrombocytopenia in Pregnancy • von Willebrand Disease (VWD) • Choosing Wisely, 15 Things Physicians and Patients should question 22 Clinical tools including: Calculators: • 4Ts Clinical Probability Scoring for HIT • Bleeding Score • Creatinine Clearance (Cockcroft-Gault) • ECOG Performance Status • EUTOS Score for CML • Factor VIII Dosage for Hemophilia • Factor XI Dosage for Hemophilia • FLIPI Scoring for Follicular Lymphoma • HCT Comorbidity Index • IPSS-R for Prognosis in MDS • MGUS Progression Risk • MIPI Scoring for Mantle Cell LymphomaMyeloma Frailty Score • R-IPI Scoring for Diffuse Large B-Cell Lymphoma • Sokal Score for CML • VTE Clinical Risk Score (Khorana) in Ambulatory Cancer Patients • Wells' Criteria for Pulmonary Embolism • Wells' Crtieria for DVT Decision Trees: • Initial Warfarin Dosing • Chronic Warfarin Dose Adjustment • VWD Assessment Algorithm • Diagnostic and Initial Treatment Algorithm for HIT • Initial Diagnostic Workup of Acute Leukemia

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CARTOX

Cellular therapies can be associated with unique, acute toxicities which can be severe or even fatal if not identified early and treated appropriately. Cytokine Release Syndrome (CRS), the most commonly observed toxicity can range in severity from low-grade constitutional symptoms to high-grade syndrome associated with life-threatening multi-organ disfunction. Neurotoxicity, originally termed CRES (CAR-Related Encephalopathy Syndrome) and now updated to ICANS (Immune effector Cell-Associated Neurotoxicity Syndrome) is the second most-common adverse even and can occur concurrently with CRS. A multi-disciplinary working group was formed to address safety issues for patients receiving cellular therapy which led to the development of new grading methods and treatment algorithms that have been incorporated into the CARTOX mobile app. The CARTOX mobile app assists with grading toxicities, managing toxicities and assists with recommendations regarding appropriate antimicrobial prophylaxis for patients who have received immune effector cell therapy. Users are more easily able to determine if the patient is having cytokine release syndrome or neurotoxicity and to grade those toxicities. Intended audience: Clinicians (physicians, nurse practitioners, physician assistants, pharmacists, nurses) who treat/care for patients receiving immune effector cells.