Learn Genetics vs CRISPR Cutout Usage & Stats
Genetics is the study of genes and tries to explain what they are and how they work. Genes are how living organisms inherit features or traits from their ancestors; for example, children usually look like their parents because they have inherited their parents' genes. Genetics tries to identify which traits are inherited, and explain how these traits are passed from generation to generation.
Genes are pieces of DNA that contain information for the synthesis of ribonucleic acids (RNAs) or polypeptides. Genes are inherited as units, with two parents dividing out copies of their genes to their offspring. Humans have two copies of each of their genes, but each egg or sperm cell only gets one of those copies for each gene. An egg and sperm join to form a complete set of genes. The resulting offspring has the same number of genes as their parents, but for any gene, one of their two copies comes from their father, and one from their mother.
Genetics
genetics, study of heredity in general and of genes in particular. Genetics forms one of the central pillars of biology and overlaps with many other areas, such as agriculture, medicine, and biotechnology.
Topics covered in the app are given below:
- Genetics news/blogs
- Genetics cells and DNA
- Health and variants
- How genes work
- Inheriting genetic condition
- Genetics and human traits
- Genetic Consultation
- Genetic Testing
- Direct to consumer genetic testing
- Gene therapy
- Genomic research
Genetics is termed as the study to understand the functioning of inheritance of traits from parents to offspring. The groundwork on which heredity stands is known as inheritance. It is defined as the procedure by which characteristics are handed down from one generation to the other. Gregor Johann Mendel is known as the “Father of Modern Genetics” for his discoveries on the basic principles of heredity.
A gene is the basic physical and functional unit of heredity. Genes are made up of DNA. Some genes act as instructions to make molecules called proteins. However, many genes do not code for proteins. In humans, genes vary in size from a few hundred DNA bases to more than 2 million bases. An international research effort called the Human Genome Project, which worked to determine the sequence of the human genome and identify the genes that it contains, estimated that humans have between 20,000 and 25,000 genes.
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CRISPR Cutout™ is the fourth in a series of mobile educational games developed by the Institute for Molecular Medicine and Infectious Disease at Drexel University College of Medicine. CRISPR Cutout introduces the molecular mechanisms of a cutting-edge genome editing technology called ‘clustered regularly interspaced short palindromic repeats’, or CRISPR for short. The player will create a gene-editing tool and use it in a cell to cut out a sequence of HIV DNA. The game has two guides called Crispy and G that will teach you how CRISPR is created and how it can be used in editing DNA to cure disease. Please visit our other games Hep B-Ware™, Malaria Invasion™, and CD4 Hunter™ to learn more about infectious diseases.
Stay tuned for more games about other microbes that threaten our health.
Follow us on Twitter: @Drexel_IMMID, #IMMID, #CD4Hunter
Visit our website: www.drexelmed.edu/immid
Game Features:
CRISPR Cutout is a fun, educational mini-game in which players create a gene-editing tool and use it in a cell to cut out a sequence of HIV DNA. The game has two guides called Crispy and G that will teach you how CRISPR can be used in editing DNA to cure disease. By immersing real science within simple gameplay, users learn about how a new and exciting gene editing tool can be used to cure infectious diseases using HIV as an example.
Download CRISPR Cutout for free to:
• Learn complex science through fast-paced and addictive gameplay.
• Learn how guide RNAs (gRNA) seek out and remove unwanted HIV from cells.
Learning Goals:
CRISPR Cutout is the fourth in a series of mini games to be developed by the Institute for Molecular Medicine and Infectious Disease at Drexel University College of Medicine, to introduce players to the world of gene editing. CRISPR Cutout was designed for non-scientists and science students. This app is awesome for use in the biomedical science curriculum in high school or in higher education. CRISPR Cutout focuses on meeting the following learning objectives:
1. Identify the nucleotides that makeup RNA and DNA.
2. Match correct nucleotides between RNA and DNA.
3. Identify Cas9 as an enzyme that can cut DNA.
4. Define gRNA.
5. Describe how Cas9 and gRNA work together to remove unwanted DNA.
Credits:
Executive Producer and Consultant
Brian Wigdahl, PhD
Chair, Department of Microbiology and Immunology (M&I); and Executive Director, Institute for Molecular Medicine and Infectious Disease (IMMID), Drexel University College of Medicine
Project Director:
Mary Ann Comunale Ed.D, M.S.
Assistant Professor (M&I); and Director, the Center for Science Communication and Outreach, Drexel University College of Medicine
Game Designers:
Mary Ann Comunale Ed.D., M.S.
Colin Page
Programmer:
Colin Page
Co-op student at M&I and IMMID, Computer Science Program, Drexel University College of Computing and Informatics
Animator and Artist:
Julia DeBenedetto
Co-op student at M&I and IMMID, Animation and Visual Effects, Drexel University College of Media Arts and Design (Class of 2018)
SPECIAL THANKS TO:
Subject Matter Experts
William Dampier, PhD; Michael Nonnemacher,
Beta Testers:
Microbiology and Immunology Department graduate students
*** Please help us improve this game by reporting any bugs to IMMID@Drexelmed.edu. We welcome feedback and suggestions for upgrades and improvements. ***
©2023 Drexel University
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Learn Genetics VS. 
CRISPR CutoutDecember 30, 2024