Single Ventricle Circulation vs KNOW Medicine Usage & Stats
This app presents a model of circulation throughout the three stages of surgical palliation for patients with single ventricle physiology, known as the Fontan sequence. An educational tool designed for medical students and anyone interested in congenital heart defects, the app allows the user to experiment with several different common surgical procedures and medical treatments, to observe the effects on clinical measures like blood pressures and oxygen delivery both at rest and during exercise, and to predict immediate post-surgical outcomes. The app displays both tabular results, and time-based blood pressure and flow waveforms and ventricular pressure-volume loops.
This app accompanies our JTCVS paper(1), which describes the circulation models used, abbreviations and settings. The paper includes details of the model mechanics, and a partial validation of model outputs vs. clinical measurements from 47 patients. This is the hand-held device app mentioned in that paper. The app provides default values for the circulation, which the user can can be customize to investigate clinical situations or patient-specific predictions. Details on the basis of the circulation model are cited in the JTCVS paper (1).
(1) Conover, T., Hlavacek, A.M., Migliavacca, F. et al. An interactive simulation tool for patient-specific clinical decision support in single ventricle physiology. J Thorac Cardiovasc Surg. 2018; 155: 712–721
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Whether you are just starting your journey, or are an experienced Hospital based practitioner… this concise resource will be your favorite Peripheral brain. Dive into the free Sample Chapters to judge for yourself!
Offering a unique expanded outline format, geared toward Students, Residents and Practitioners of Medicine in all its fields. A blend of organ system based pathophysiology, including detailed treatment and pharmacology sections with a focus on essential high yield knowledge, allowing for a deeper level of understanding and retention.
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Read through the many on-line reviews. Prior print and ebook versions were under the title ‘The Consult Manual of Internal Medicine’ being rebranded for this 4th, and never-ending app version
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Single Ventricle Circulation VS. 
KNOW MedicineJanuary 1, 2025